Ka whakamahia te Cyclopropyl 2-fluorobenzyl ketone hei takawaenga o Prasugrel.
Ko te Prasugrel he antiplatelet thiophenopyridine i whakawhanakehia e Eli Lilly me daiichisankyo, he kaihanga rongoa Hapanihi.He rongoa kaamua.Ka hangaia he ngota ngota kaha i muri i te paopaotanga na roto i te cytochrome P450 i roto i te ate, ka hono atu ki te kaiawhina pereti P2Y12 kia kaha ai ki te whakahiato pereti.Kua whakaatuhia e nga rangahau haumanu he pai ake te paanga anticoagulant o te horopeta 60 mg i te 300 mg te horopeta paerewa me te 600 mg te nui ake o te horopeta o te clopidogrel, ka taea te whakaiti i te mate o te mate o te ngakau, te whiu me te mate na te mate o te ngakau ma te 20%, me te whai hua tere. , he pai te painga whakaora, he pai te aukati tarukino me te koiora, me te paitini iti.
JIN DUN Medical kuaKo te tohu ISO me te whakatutuki i nga paerewa whakaputa GMP, e mahi ana i nga tohunga whakahiato raau taero o roto me tawahi me te whai wheako nui hei arahi i te R&D a te kamupene.
TE WHAKAMAHI OGY
●High Pressure Catalytic Hydrogenation .Tauhohenga Hydrogenolysis High Pressure.Tauhohenga Cryogenic (<-78%C)
●Hangai Heterocyclic Aromatic
●Rearrangement Reaction
●Tauira Hira
●Heck, Suzuki,Negishi,Sonogashira .Tauhohenga Gignard
Nga taputapu
He maha nga taputapu whakamatautau me te whakamatautau, penei i te: NMR (Bruker 400M) 、HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Te Ngaruiti Ngaruiti, Te Whakarara Whakarara, Te Waahanga Matawai Rereke (DSC), Te Kaitiaki Irahiko...
R&D Team
Kei a Jindun Medical he roopu o nga kaimahi R&D ngaio, a he maha nga tohunga whakahiato tarukino o roto me nga iwi ke ki te arahi i te R&D, kia tika ake ai, kia pai ake ai to taatau whakahiato.
Kua awhinahia e matou etahi kamupene rongoa o roto, penei iHansoh, Hengrui me HEC Pharm.I konei ka whakaatuhia e matou tetahi waahanga o ratou.
Whakaritenga Take Tuatahi:
Nama nama: 110351-94-5
Take Whakaritea Tuarua:
Nama nama: 144848-24-8
Ritenga Take Tuatoru:
Nama cas: 200636-54-0
1.Whakaritea nga Takawaenga Hou, API ranei.He rite ano ki te tiritiri keehi i runga ake nei, kei nga kaihoko nga tono mo nga Kaiwawao motuhake, API ranei, a kaore e kitea nga hua e hiahiatia ana i te maakete, katahi ka awhina taatau ki te Whakaritea.
2.Tukatuka Arotautanga mo nga Hua Tawhito.Ka awhina to taatau roopu ki te Whakapaipai me te whakapai ake i nga mahi penei kua tawhito te huarahi tauhohenga, he nui te utu whakaputa, he iti te mahi.Ka taea e matou te whakarato i nga tuhinga katoa mo te whakawhiti hangarau me te whakapai ake i te tukanga, awhina i te kaihoko mo te mahi pai ake.
Mai i nga whaainga tarukino ki nga IND, ka tukuna e JIN DUN Medical ki a koenga otinga R&D motuhake kotahi-mutu.
Kei te tohe a JIN DUN Medical ki te hanga i tetahi roopu me nga moemoea, ki te hanga i nga hua rangatira, ki te tino mohio, ki te kaha, me te mahi katoa hei hoa pono me te hoa o nga kaihoko!