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2-deoxy-2',2'-difluoro-3'5'-bis-o-benzoyleytidi me te monohydrochloride

2-deoxy-2',2'-difluoro-3'5'-bis-o-benzoyleytidi me te monohydrochloride

Whakaahuatanga Poto:

CAS no:134790-39-9

Nga taonga matū: Gemcitabine Intermediates


Taipitopito Hua

Tohu Hua

Whakamahinga

Ka whakamahia te 2-deoxy-2',2'-difluoro-3'5'-bis-o-benzoyleytidi ne monohydrochloride hei takawaenga o Gemcitabine.
Ko te Gemcitabine he pirimidine nucleotide analogue, no nga raau taero anticancer anticancer.Ka taea e ia te aukati i te ahunga whakamua o te whakahiato DNA i roto i tetahi waa, ara, te wahanga-S.Kei a ia nga ahuatanga o te whanui anticancer spectrum, te tikanga ahurei o te mahi, te paitini iti, kaore he parenga whakawhiti ki etahi atu raau taero chemotherapeutic me te kore he superposition o te paitini.I tenei ra, kua whakaaetia te gemcitabine mo te whakamahi i roto i nga whenua neke atu i te 90, ka noho hei rongoa tuatahi mo te maimoatanga o te mate pukupuku mate pukupuku iti-iti me te "paerewa koura" mo te maimoatanga o te mate pukupuku pancreatic.


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