Rivaroxaban（S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban（S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Ka whakamahia i roto i nga turoro pakeke e whiriwhiri ana i te hipoki hipoki, turi ranei hei whakakapi hei aukati i te thrombosis venous (VTE).
Ka whakamahia ki te aukati, ki te whakaiti ranei i te hanga o te thrombosis, te thrombosis uaua hohonu (DVT) me te pulmonary embolism (PE) i muri i te pokanga whakakapi hipoki, turi ranei.
Ko te horopeta e taunakitia ana ko te rivaroxaban oral 10mg, kotahi ia ra.Rivaroxaban 10mg ka taea te tango me te kai me te takitahi ranei.Rivaroxaban 15mg ranei 20mg papa me tango ki te kai.
paerewa: usp40
Te whakamatautau: 99-102%
Waho: Te paura ma
Mōkī: 25kg/drum
Tangohia te 4-(4-aminophenyl) morpholin-3-one (SM-1), (S)-N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) te mea timatanga .I muri i te condensation, cyclization, aminolysis and acylation, ka whiwhihia te rivaroxaban crude, ka parahia te rivaroxaban kua oti.
Te Takanga: Ko tenei hua he papa whero kua pania ki te kiriata.
Apatoko:
Papa papa: microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, hypromellose, konutai lauryl sulfate, konupora stearate
Te paninga: polyethylene glycol, hypromellose, titanium dioxide, rino waikura whero
Ko te Rivaroxaban he rongoa tino whiriwhiri, he rongoa waha e aukati tika ana i te take Xa.Na roto i te aukati tino whiriwhiri me te whakataetae whakataetae o te tauwehe kore utu me te here Xa me te mahi prothrombin, ka whakaroahia te waahanga thromboplastin time plate (PT) me te wa prothrombin (aPTT) i runga i te tikanga e whakawhirinaki ana ki te horopeta, ka taea te aukati i te wairere coagulation Ko nga ara endogenous me te ara o waho. ka aukati i te hanga o te thrombin me te thrombosis.Kaore a Rivaroxaban e aukati i te thrombin (tauwehe whakahohe Ⅱ), kaore ano kia whai paanga ki nga platelets.
Ko te rereketanga nui i waenga i te rivaroxaban me te fondaparinux/heparin ko te kore e hiahiatia kia uru mai te antithrombin III ka taea te whakahē tika i te tauwehe kore utu me te here Xa;i te wa e hiahiatia ana e te heparin te antithrombin III ki te mahi, a, kaore he paanga ki te take Xa i roto i te matatini prothrombin.
JIN DUN Medical kuaKo te tohu ISO me te whakatutuki i nga paerewa whakaputa GMP, e mahi ana i nga tohunga whakahiato raau taero o roto me tawahi me te whai wheako nui hei arahi i te R&D a te kamupene.
TE WHAKAMAHI OGY
●High Pressure Catalytic Hydrogenation .Tauhohenga Hydrogenolysis High Pressure.Tauhohenga Cryogenic (<-78%C)
●Hangai Heterocyclic Aromatic
●Rearrangement Reaction
●Tauira Hira
●Heck, Suzuki,Negishi,Sonogashira .Tauhohenga Gignard
Nga taputapu
He maha nga taputapu whakamatautau me te whakamatautau, penei i te: NMR (Bruker 400M) 、HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Te Ngaruiti Ngaruiti, Te Whakarara Whakarara, Te Waahanga Matawai Rereke (DSC), Te Kaitiaki Irahiko...
R&D Team
Kei a Jindun Medical he roopu o nga kaimahi R&D ngaio, a he maha nga tohunga whakahiato tarukino o roto me nga iwi ke ki te arahi i te R&D, kia tika ake ai, kia pai ake ai to taatau whakahiato.
Kua awhinahia e matou etahi kamupene rongoa o roto, penei iHansoh, Hengrui me HEC Pharm.I konei ka whakaatuhia e matou tetahi waahanga o ratou.
Whakaritenga Take Tuatahi:
Nama nama: 110351-94-5
Take Whakaritea Tuarua:
Nama nama: 144848-24-8
Ritenga Take Tuatoru:
Nama cas: 200636-54-0
1.Whakaritea nga Takawaenga Hou, API ranei.He rite ano ki te tiritiri keehi i runga ake nei, kei nga kaihoko nga tono mo nga Kaiwawao motuhake, API ranei, a kaore e kitea nga hua e hiahiatia ana i te maakete, katahi ka awhina taatau ki te Whakaritea.
2.Tukatuka Arotautanga mo nga Hua Tawhito.Ka awhina to taatau roopu ki te Whakapaipai me te whakapai ake i nga mahi penei kua tawhito te huarahi tauhohenga, he nui te utu whakaputa, he iti te mahi.Ka taea e matou te whakarato i nga tuhinga katoa mo te whakawhiti hangarau me te whakapai ake i te tukanga, awhina i te kaihoko mo te mahi pai ake.
Mai i nga whaainga tarukino ki nga IND, ka tukuna e JIN DUN Medical ki a koenga otinga R&D motuhake kotahi-mutu.
Kei te tohe a JIN DUN Medical ki te hanga i tetahi roopu me nga moemoea, ki te hanga i nga hua rangatira, ki te tino mohio, ki te kaha, me te mahi katoa hei hoa pono me te hoa o nga kaihoko!
![Casp ungin Acetate;Caspofungin acetate;Cancidas;Caspofungin acetate [USAN:BAN:JAN];](http://cdn.globalso.com/jindunchem-med/fbe17385-300x300.jpg)