I whakatapua ki te whakahaere tino pai me te kamupene kaihoko whai whakaaro, he maha nga wa e waatea ana o maatau kaimahi mohio ki te korero mo o hiahia me te tino koa ki te kaihoko mo te Whakarato Whakamaramatanga 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' kua reri ano ki te mahi tahi me nga hoa pai hinonga mai i to whare me tawahi kia pai ai te noho tahi.
I whakatapua ki te whakahaere tino pai me te kamupene kaihoko whai whakaaro, he maha nga wa e waatea ana o maatau hoa kaimahi mohio ki te korero mo o hiahia me te pai ki te kaihoko.Haina Imidazole me Imz, Ia tau, he maha o taatau kaihoko ka toro atu ki ta maatau kamupene me te whakatutuki i nga ahunga whakamua pakihi e mahi tahi ana me matou.Ka tino mihi matou ki a koe ki te toro mai ki a matou i nga wa katoa ka eke tahi matou ki te angitu i roto i te umanga makawe.
Te takawaenga mo te whakahiato o te allopurinol.
Koia tetahi o nga raupapa pyrazole 3-amino-4-substituted.Ka taea te whakamahi hei takawaenga ki te whakahiato i te maha o nga puhui pararopi whai hua mo te rongoa, penei i te allopurinol, tetahi o nga raupapa pärönaki pyrazolopyrimidine, ko te whakamutunga mai i te tau 1963 Mai i tana whakamahinga haumanu, ko ia te rongoa matua mo te maimoatanga o te kauti.I tenei wa, he iti noa nga tikanga mo te whakahiato
Ko te 3-aminopyrazole-4-carboxamide hemisulfate i Haina, ko te nuinga ma te whakahoki i te malononitrile me te triethyl orthoformate ki te whakarite i te ethoxymethylene malononitrile, katahi me te Ko te tauhohenga o te hydrazine hydrate ka puta te 3-amino-4-cyanopyrazole, ka mutu te tauhohenga ki te waikawa waikawa konutai.
3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), te katoa o nga hua o te Ko te whakahiatotanga ma tenei tikanga e tata ana ki te 60% (kua tatauhia hei malononitrile), ko tenei tikanga Ka uru ki te tauhohenga e toru-taahiraa, he roa ake nga hikoi, me nga reagents e whakamahia ana, penei i te malononitrile me te ethoxymethylene malononitrile, he paitini me te utu nui.I tua atu, ko te 3-aminopyrazole-4 kua whakaritea e tenei tikanga -Formamide hemisulfate he tae he uaua ki te tango me te hiahia ki te tukatuka atu, he mea uaua ake.
He purongo kei roto i nga tuhinga o tawahi e whakamahi ana i te pyridylamide hydrazone me te ethoxymethylene malononitrile hei rauemi mata hei whiwhi 3-amino-4-cyanopyrazole ma te taapiri me te cyclization, katahi ka tauhohe ki te waikawa sulfuric concentrated ki te whiwhi i te pūhui ūnga (Reuken G Jones. Reactions of orthoesters with pūhui activemethylene [J] J Am Chem Soc. 1952,74(5) :4889 4891).Ko nga rauemi matua e whakamahia ana i roto i tenei tikanga he utu nui, kaore i te nui te hua o te tauhohenga, me te iti o te hua o te mahi ahumahi.Me uaua.
Paerewa Kaiwhakahaere:Paerewa hinonga
Waho:Te paura ma, kowhai ranei
Mōkī:25kg/pahū
whakamātautau (HPLC) ihirangi He nui ake i te rite ranei ki te 98.0%
parakore (HPLC) ihirangi Nui ake i te rite ranei ki te 99.5%
I whakatapua ki te whakahaere tino pai me te kamupene kaihoko whai whakaaro, he maha nga wa e waatea ana o maatau kaimahi mohio ki te korero mo o hiahia me te tino koa ki te kaihoko mo te Whakarato Whakamaramatanga 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' kua reri ano ki te mahi tahi me nga hoa pai hinonga mai i to whare me tawahi kia pai ai te noho tahi.
Te whakamarama teiteiHaina Imidazole me Imz, Ia tau, he maha o taatau kaihoko ka toro atu ki ta maatau kamupene me te whakatutuki i nga ahunga whakamua pakihi e mahi tahi ana me matou.Ka tino mihi matou ki a koe ki te toro mai ki a matou i nga wa katoa ka eke tahi matou ki te angitu i roto i te umanga makawe.