Ka whakamahia te Guanosine hei takawaenga o Valaciclovir.
Ko Valacyclovir he guanine analogue antiviral tarukino.Kei te whakamahia i roto i te maimoatanga haumanu o te herpes simplex me te mate herpes zoster i roto i nga mate o te taatai.Ko tenei hua te tohu o te acyclovir.Ka tere te ngongo i muri i te whakahaere a-waha, ka tere te huri hei acyclovir i roto i te tinana.Ko tana painga antiviral e takarohia ana e te acyclovir.Whai muri i te urunga o te acyclovir ki nga pūtau kua pangia e te herpes, ka whakataetae ia ki te deoxynucleoside mo te huaketo thymidine deoxynucleoside kinase, kinase pūtau ranei, ka whakapouritia te tarukino ki te acyclic guanosine triphosphate.Hei tïpako o te tukurua huaketo, ka whakataetae te acyclovir me te deoxyguanine triphosphate mo te DNA polymerase huaketo, e aukati ana i te whakahiatotanga o te DNA huaketo me te whakaatu i te paanga pareketo.Ko te mahi antiviral o tenei hua i roto i te vivo he pai ake i te acyclovir, a ko te tohu maimoatanga o te herpes simplex huaketo momo I me te momo II he 42.91% me te 30.13% teitei ake i te acyclovir.He nui hoki te mana whakaora ki te huaketo varicella zoster.
JIN DUN Medical kuaKo te tohu ISO me te whakatutuki i nga paerewa whakaputa GMP, e mahi ana i nga tohunga whakahiato raau taero o roto me tawahi me te whai wheako nui hei arahi i te R&D a te kamupene.
TE WHAKAMAHI OGY
●High Pressure Catalytic Hydrogenation .Tauhohenga Hydrogenolysis High Pressure.Tauhohenga Cryogenic (<-78%C)
●Hangai Heterocyclic Aromatic
●Rearrangement Reaction
●Tauira Hira
●Heck, Suzuki,Negishi,Sonogashira .Tauhohenga Gignard
Nga taputapu
He maha nga taputapu whakamatautau me te whakamatautau, penei i te: NMR (Bruker 400M) 、HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Te Ngaruiti Ngaruiti, Te Whakarara Whakarara, Te Waahanga Matawai Rereke (DSC), Te Kaitiaki Irahiko...
R&D Team
Kei a Jindun Medical he roopu o nga kaimahi R&D ngaio, a he maha nga tohunga whakahiato tarukino o roto me nga iwi ke ki te arahi i te R&D, kia tika ake ai, kia pai ake ai to taatau whakahiato.
Kua awhinahia e matou etahi kamupene rongoa o roto, penei iHansoh, Hengrui me HEC Pharm.I konei ka whakaatuhia e matou tetahi waahanga o ratou.
Whakaritenga Take Tuatahi:
Nama nama: 110351-94-5
Take Whakaritea Tuarua:
Nama nama: 144848-24-8
Ritenga Take Tuatoru:
Nama cas: 200636-54-0
1.Whakaritea nga Takawaenga Hou, API ranei.He rite ano ki te tiritiri keehi i runga ake nei, kei nga kaihoko nga tono mo nga Kaiwawao motuhake, API ranei, a kaore e kitea nga hua e hiahiatia ana i te maakete, katahi ka awhina taatau ki te Whakaritea.
2.Tukatuka Arotautanga mo nga Hua Tawhito.Ka awhina to taatau roopu ki te Whakapaipai me te whakapai ake i nga mahi penei kua tawhito te huarahi tauhohenga, he nui te utu whakaputa, he iti te mahi.Ka taea e matou te whakarato i nga tuhinga katoa mo te whakawhiti hangarau me te whakapai ake i te tukanga, awhina i te kaihoko mo te mahi pai ake.
Mai i nga whaainga tarukino ki nga IND, ka tukuna e JIN DUN Medical ki a koenga otinga R&D motuhake kotahi-mutu.
Kei te tohe a JIN DUN Medical ki te hanga i tetahi roopu me nga moemoea, ki te hanga i nga hua rangatira, ki te tino mohio, ki te kaha, me te mahi katoa hei hoa pono me te hoa o nga kaihoko!