4-Methoxybenzylalkohol;ANISALKOHOL;4-methoxy-benzenemetano;

Takawaenga mo Moxonidine
Ka taea te whakahihiko i nga kaiwhakawhiwhi α2 o te pokapū ka puta nga paanga antihypertensive, he rite ki te clonidine.Ko te tere o te whakauru-waha (90%) me te koiora (88%) e rua teitei, a kaore he paanga tuatahi.Ko te kukū toto teitei ka puta 1 ki te 3 haora i muri i te tango i te tarukino.Ko te nuinga ka peia e nga whatukuhu.t1/2 he 2 haora pea.Ka whakamahia te haumanu mo te whakaheke toto.

Te wai kore tae, paku kowhai ranei.Ko te rewa ko te 23-25.5°C, ko te 159°C te ira koropuke, ko te kiato whanaunga ko te 1.113 (15/15°C), ko te taurangi whakaata he 1.5442.He ngawari te rewa ki te waipiro me te etera, tata kore e rewa ki te wai.

Ko tenei hua he kakara reka o te fennel, he maha nga wa e whakamahia ana ki te whakarite i te jasmine, te lilac me etahi atu mea kakara, a he pai mo te whakarite hinu kakara.He mea kakara tenei hua e whakaaetia ana e te GB2760-86 o taku whenua.Ka whakamahia te nuinga ki te whakarite i nga mea reka penei i te vanilla, te tiakarete, te koko, te aramona, me te pītiti.Kei te whakamahia hoki i roto i te whakahiato pararopi me te whakarewa.

Na te whakahekenga o te anisaldehyde.Ka tauhohe a Cannizzaro ki te anihi, te formaldehyde me te konutai waihā i roto i te waihā hei whakaputa i te waipiro p-methoxybenzyl.

Whai muri i te whakahokinga mai o te waihano ma te whakamaarama, ka tangohia te paparanga hinu i te tauhohenga me te benzene, ka whakakawatia ma te taapiri i te waikawa acetic, katahi ka whakakorehia ki te konutai bicarbonate ki te kawakore ngoikore.I muri i te horoinga ki te wai ki te korekore, ka whakahokia mai te benzene ma te whakamarumaru, a ka tukuna te toenga ki te whakakorenga korehau kia whiwhi ai te waipiro p-methoxy Benzyl.

Ka mahi ma te whakaihiihi i nga α2-receptors presynaptic pokapū.He rite te awenga antihypertensive ki te nifedipine antagonist calcium me te ACE inhibitor captopril.Ka whakamahia mo te whakaheke toto.