3-(1-(Dimethylamino)ethyl]phenol

Ka whakamahia te 3-(1-(Dimethylamino)ethyl]phenol hei takawaenga o Rivastigmine tartrate .
Ko te Rivastigmine tartrate he rivastigmine nga raau mate a Alzheimer, ko te rivastigmine he physostigmine derivative na Novartis mo te wa tuatahi i pai te whakawhanake i te ingoa hokohoko Exelon (exelon), he ngota kei reira te hanganga carbamate, he momo waikawa amino o te aukati cholinesterase cerebral whiriwhiri, ka taea hoki te aukati. Ko te acetylcholinesterase me te butyrylcholinesterase, nga neurons cholinergic na roto i te whakaroa i te tukunga o te whakahekenga acetylcholine me te kaha e whakatairanga ana i te whakahaerenga nerve cholinergic, ka taea te whakapai ake i nga raruraru mahi hinengaro i takawaengahia e te cholinergic, na reira ka pai ake te mahi hinengaro o nga turoro mate o Alzheimer.He ngoikore te herenga pūmua plasma Rivastigmine, he ngawari ki roto i te arai toto-roro, he nui te tohu o te whiriwhiringa o te roro.Ehara i te mea ko te mahi maataki noa i runga i te uho roro me te hippocampus e tino pa ana, engari he pai ake te aukati i te momo-iti o te AChE i roto i te roro, na te mea ka heke te kaha o nga paanga taha cholinergic peripheral.Ko te Rivastigmine i roto i te vivo haurua-ora he poto me te roa o te mahi.Kaore i rite ki te tacrine, he kaha ake tenei hua i roto i te hippocampus me te uho o te G1 enzyme aukati.Ko te whare haumanu mo te maimoatanga o te ahua ngoikore o te ahua Alzheimer, te mate Alzheimer ranei ka whakapaehia he mate a Alzheimer.