2'-Methoxy-3'-nitro-biphenyl-3-carboxylic acid

Ka whakamahia te waikawa 2'-Methoxy-3'-nitro-biphenyl-3-carboxylic hei takawaenga o Eltrombopag .
Ko Eltrombopag, i whakawhanakehia e GlaxoSmithKline (GSK) i te UK me muri mai i whakawhanakehia tahi me Novartis i Switzerland, ko te tuatahi, ko te iti noa iho te whakangao ngota iti kore peptide TPO agonist i te ao.I whakaaetia a Eltrombopag e te US FDA i te 2008 mo te maimoatanga o te idiopathic thrombocytopenic purpura (ITP), me te 2014 mo te maimoatanga o te anemia aplastic nui (AA).Koia hoki te rongoa tuatahi i whakaaetia e te US FDA mo te maimoatanga o AA i nga tau 30 tata nei.
I roto i Hakihea2012, te US FDA whakaaetia Eltrombopag mo te maimoatanga o te thrombocytopenia i roto i tūroro ki te kakā C (CHC) mau tonu, kia taea e tūroro kakā C ki te matapae rawakore e tika ana ki te iti platelet tatau tīmata me te mau tonu interferon hāngai therapy paerewa mō mate ate.I te Hui-tanguru 3, 2014, i kii a GlaxoSmithKline i tukuna e te FDA te tohu rongoa rongoa rongoa a Eltrombopag mo te maimoatanga o te hemopenia i roto i nga turoro e mate ana i te anemia aplastic pukapuka matū nui (SAA) kaore i tino aro ki te rongoa mate.I te Akuhata 24, 2015, ka whakaaetia e te US FDA a Eltrombopag mo te maimoatanga o te thrombocytopenia i roto i nga pakeke me nga tamariki 1 tau me te neke atu me te thrombocytopenia ārai mate mau tonu (ITP) he iti rawa te whakautu ki nga corticosteroids, immunoglobulins, splenectomy ranei.I te Hanuere4,2018, i whakaaetia a Eltrombopag kia whakarārangihia ki Haina mo te maimoatanga o te thrombocytopenia aukati tuatahi (ITP).